Atypical rapid onset Scleroderma Renal Crisis (SRC) complicated with diffuse alveolar hemorrhage and pleuro-pericardial effusions in a patient with recently diagnosed breast cancer and a positive anti-RNA polymerase III Ab.: A case report
| Autor: | Fuad Zeid, Ibrahim Shahoub, Iheanyichukwu Ogu, Emhemmid Karem, Obadah Aqtash, Hazim Bukamur |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Pleural effusion Scleroderma Renal Crisis Pericardial effusion Case Report Malignancy Gastroenterology 03 medical and health sciences Scleroderma renal crisis 0302 clinical medicine Pulmonary-renal syndrome Breast cancer Internal medicine medicine Positive anti-RNA polymerase III Ab 030212 general & internal medicine skin and connective tissue diseases 030203 arthritis & rheumatology lcsh:RC705-779 business.industry Diffuse alveolar hemorrhage lcsh:Diseases of the respiratory system medicine.disease Systemic sclerosis Complication business |
| Zdroj: | Respiratory Medicine Case Reports, Vol 25, Iss, Pp 137-141 (2018) Respiratory Medicine Case Reports |
| ISSN: | 2213-0071 |
| Popis: | Scleroderma associated Pulmonary–Renal Syndrome is a rare but severe complication with a poor prognosis and high mortality. A high index of suspicion is needed for early recognition of this potential complication in patients with systemic sclerosis and institution of appropriate treatment. With more data showing an increased association between scleroderma and malignancy, a heightened vigilance should also be exercised in patients with malignancy and scleroderma-like presentation. We report of a case rapid onset systemic sclerosis complicated by acute renal failure and diffuse alveolar hemorrhage in a woman with stage IIB right breast cancer and elevated RNA Polymerase III IgG Ab. To our knowledge, this the first case of a patient with breast cancer associated with systemic sclerosis and pulmonary-renal syndrome. Keywords: Systemic sclerosis, Pulmonary-renal syndrome, Scleroderma renal crisis, Diffuse alveolar hemorrhage, Breast cancer, Positive anti-RNA polymerase III Ab, Pleural effusion, Pericardial effusion |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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