Regional Diastolic Contour Abnormalities During Contrast Stress Echocardiography: Improved Detection of Coronary Artery Disease
| Autor: | Jo Ellen Ehrsam, Sabino Iliceto, Sharon L. Mulvagh, Lori A. Carlson, Sonja Cukon-Buttignoni, Marion E. Barnes, Mary E. Hagen, Sahar S. Abdelmoneim |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty media_common.quotation_subject Diastole Contrast Media Coronary Artery Disease Sensitivity and Specificity Coronary artery disease Ventricular Dysfunction Left Internal medicine medicine Stress Echocardiography Humans Contrast (vision) Radiology Nuclear Medicine and imaging media_common Fluorocarbons Framingham Risk Score business.industry Reproducibility of Results Middle Aged Image Enhancement medicine.disease Confidence interval Stenosis Echocardiography Relative risk Exercise Test Cardiology Female Radiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of the American Society of Echocardiography. 21:1109-1115 |
| ISSN: | 0894-7317 |
| DOI: | 10.1016/j.echo.2008.07.018 |
| Popis: | Background Use of contrast improves detection of systolic regional wall motion abnormalities (RWMAs) during stress echocardiography. We evaluated regional diastolic contour abnormalities (RDCAs) that were associated with coronary artery disease (CAD). Methods From August of 2003 to September of 2004, we evaluated 89 patients who underwent contrast stress echocardiography (CSE) and coronary angiography within a 3-month period (“invasive” group) and 17 patients with lower CAD risk who underwent CSE only (“reference” group). Results RDCAs were present in 73 patients in the invasive group and were associated with higher Framingham risk scores (relative risk, 3.6; 95% confidence interval, 1.9-6.6). RDCAs were present in 1 patient in the reference group. When combined with RWMA, RDCA improved sensitivity of CSE from 78% to 97% and specificity from 26% to 59% (diagnostic threshold for CAD was 70% stenosis). Conclusion RDCAs were a novel observation associated with higher CAD risk and improved the diagnostic accuracy of CSE. |
| Databáze: | OpenAIRE |
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