The effects of different epidural analgesia formulas on labor and mode of delivery in nulliparous women
| Autor: | Li-Kuei Chen, Ya Min Yang, Yu Hsuan Yang, Chien-Nan Lee, Pei-Lin Lin, Shou-Zen Fan, Shin Yan Chen |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
lcsh:Gynecology and obstetrics Loading dose Instrumental delivery Group B Fentanyl anesthetics local (ropivacaine) Pregnancy Obstetrics and Gynaecology medicine Humans analgesic techniques (epidural) Ropivacaine Prospective Studies Anesthetics Local Prospective cohort study lcsh:RG1-991 Labor Pain Bupivacaine Cesarean Section business.industry Obstetrics and Gynecology analgesia Analgesia Patient-Controlled Amides Analgesia Epidural Analgesics Opioid Parity patient-controlled analgesic techniques Treatment Outcome Mode of delivery Anesthesia Analgesia Obstetrical Female anesthetics local (bupivacaine) business medicine.drug |
| Zdroj: | Taiwanese Journal of Obstetrics & Gynecology, Vol 53, Iss 1, Pp 8-11 (2014) |
| ISSN: | 1028-4559 |
| DOI: | 10.1016/j.tjog.2012.01.039 |
| Popis: | Objectives Patient-controlled epidural analgesia (PCEA) and continuous epidural infusion (CEI) are popular and effective methods for pain relief during labor; however, there are concerns about increasing rates of cesarean section (C/S) and instrumental delivery. This prospective study investigated the effect of PCEA and CEI with different formulas on labor and the mode of delivery in nulliparous women. Materials and methods A total of 480 nulliparous women were randomized into four groups, with 120 in each. Group A received a loading dose of 10 mL of 1 mg/mL ropivacaine with 2 μg/mL fentanyl, then an intermittent bolus of 5 mL with a background infusion of 5 mL/hour by PCEA. Group B received the same PCEA formula as Group A with 0.8 mg/mL bupivacaine. Group C received the same formula as Group A by CEI with 1 mg/mL ropivacaine at a rate of 10 mL/hour. Group D received the same formula as Group C with 0.8 mg/mL bupivacaine. The rates of C/S and instrumental delivery and the incidence of side effects were recorded. Results The rates of C/S were significantly different between Groups A and C, Groups A and D, and Groups B and D. The rates of instrumental delivery for normal spontaneous delivery were significantly different between Groups A and B, A and D, B and C, and C and D. Conclusion The C/S rate was higher in Groups C and D; however, the instrumental delivery rate was lower in Groups A and C. We conclude that PCEA with 1 mg/mL ropivacaine might provide the greatest benefit for labor analgesia. |
| Databáze: | OpenAIRE |
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