An outbreak of hepatitis A in young adults in central Italy
| Autor: | Tommaso Stroffolini, M. Divizia, W. Biagini, G. P. Palazzesi, R. F. Frongillo, L. Lorenzoni |
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| Jazyk: | angličtina |
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Adolescent Epidemiology Settore MED/42 - Igiene Generale e Applicata Attack rate Disease Outbreaks Age groups Risk Factors Medicine Animals Humans Young adult business.industry Water Microbiology Italy Bivalvia Food Microbiology Case-Control Studies Hepatitis A Female Outbreak Mean age medicine.disease business |
| Popis: | Between September, 1988 and January, 1989 a common source outbreak of 47 cases of serologically confirmed hepatitis A occurred in a town of central Italy. Thirty-eight cases were primary, three co-primary and six secondary. The highest age-specific attack rate was seen in subjects aged 15-24 years (120 per 100,000); the mean age of cases was 24.6 years and the median age was 22 years. A matched triplet case-control study showed significant association between the disease and consumption of either raw mussels (41% of cases, compared with 10% of controls; P less than 0.0001) or a single brand of mineral water (63% of cases, compared with 41% of controls; P less than 0.05). The mean age of the cases reflects the shift in primary susceptibility to the infection from younger to older age groups, a finding which has recently been demonstrated by several seroepidemiological surveys in Italy. |
| Databáze: | OpenAIRE |
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