In vitro efficacy of a 0.2% polyhexamethylene biguanide‐impregnated gauze dressing against pathogenic bacterial isolates found in horses
| Autor: | Barbara A. Byrne, Charlene V. Noll, Jorge E. Nieto, Isabelle Kilcoyne, Timothy Thio |
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| Rok vydání: | 2021 |
| Předmět: |
040301 veterinary sciences
Staphylococcus Biguanides Bacterial growth medicine.disease_cause Microbiology Incubation period 0403 veterinary science Agar plate 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine In vivo Escherichia coli Animals Surgical Wound Infection Medicine Horses Escherichia coli Infections General Veterinary biology business.industry Pseudomonas aeruginosa 04 agricultural and veterinary sciences Staphylococcal Infections biology.organism_classification Bandages chemistry 030220 oncology & carcinogenesis Horse Diseases Growth inhibition business Bacteria Disinfectants |
| Zdroj: | Veterinary Surgery. 50:880-887 |
| ISSN: | 1532-950X 0161-3499 |
| Popis: | OBJECTIVE To determine the ability of 0.2% polyhexamethylene biguanide (PHMB)-impregnated gauze to inhibit the growth of bacteria isolated from equine infected sites. STUDY DESIGN In vitro study. METHODS Nine bacterial isolates were obtained from cultures submitted from equine patients presenting with penetrating injuries of the hoof (n = 4), septic osteitis (n = 1), synovial sepsis (n = 1), wounds (n = 2), and incisional infection following laparotomy (n = 1). Two standardized strains were also included. A standard inoculum of each isolate was placed on 12 Muller-Hinton agar plates. Squares (2.5 cm × 2.5 cm) of 0.2% PHMB-impregnated (n = 6) and nonimpregnated control gauze (n = 6) were placed on inoculated agar plates. Bacterial growth under each gauze square was assessed after a 24-h incubation period and areas of inhibition were measured to a standardized scale, using image-processing software. Mean ± SD growth inhibition (%) using 0.2% PHMB-impregnated gauze was compared to the nonimpregnated gauze for each isolate using Student's t test (p |
| Databáze: | OpenAIRE |
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