Interoperative Biopsy Site Relocalization in Endoluminal Surgery
| Autor: | Adrien Sportes, Anant Vemuri, Stéphane Nicolau, Luc Soler, Nicholas Ayache, Jacques Marescaux |
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| Přispěvatelé: | L'Institut hospitalo-universitaire de Strasbourg (IHU Strasbourg), Institut National de Recherche en Informatique et en Automatique (Inria)-l'Institut de Recherche contre les Cancers de l'Appareil Digestif (IRCAD)-Les Hôpitaux Universitaires de Strasbourg (HUS)-La Fédération des Crédits Mutuels Centre Est (FCMCE)-L'Association pour la Recherche contre le Cancer (ARC)-La société Karl STORZ, Analysis and Simulation of Biomedical Images (ASCLEPIOS), Inria Sophia Antipolis - Méditerranée (CRISAM), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria), Institut de Recherche Contre les Cancers de l'Appareil Digestif-European Institute of Telesurgery (IRCAD/EITS) |
| Rok vydání: | 2016 |
| Předmět: |
Image-Guided Biopsy
Natural Orifice Endoscopic Surgery Electromagnetics Swine 0206 medical engineering Biomedical Engineering Margin of error 02 engineering and technology Tracking (particle physics) Sensitivity and Specificity Synthetic data 030218 nuclear medicine & medical imaging Magnetics 03 medical and health sciences Esophagus 0302 clinical medicine Biopsy Site electromagnetic tracking [INFO.INFO-IM]Computer Science [cs]/Medical Imaging Animals Medicine Barrett's Oesophagus Computer vision [INFO.INFO-BT]Computer Science [cs]/Biotechnology Ground truth Microscopy Video business.industry gastro-intestinal (GI) endoscopy Esophagoscopes Reproducibility of Results Equipment Design Computer assisted intervention 020601 biomedical engineering Equipment Failure Analysis biopsy relocalization video synchronization Trajectory Noise (video) Artificial intelligence business |
| Zdroj: | IEEE Transactions on Biomedical Engineering IEEE Transactions on Biomedical Engineering, 2016, 63 (9), pp.1862-1873. ⟨10.1109/TBME.2015.2503981⟩ |
| ISSN: | 1558-2531 0018-9294 |
| DOI: | 10.1109/tbme.2015.2503981 |
| Popis: | International audience; Barrett's oesophagus, a pre-malignant condition of the oesophagus has been on a rise in the recent years. The standard diagnostic protocol for Barrett's involves obtaining biopsies at suspicious regions along the oesophagus. The localization and tracking of these biopsy sites " inter-operatively " poses a significant challenge for providing targeted treatments and tracking disease progression. This paper proposes an approach to provide guided navigation and relocalization of the biopsy sites using an electromagnetic tracking system. The characteristic of our approach over existing ones is the integration of an EM sensor at the flexible endoscope tip, so that the endoscopic camera depth inside the oesophagus can be computed in real-time, allowing to retrieve and display an image from a previous exploration at the same depth. We firstly describe our system setup and methodology for inter-operative registration. We then propose three incremental experiments of our approach. First, on synthetic data with realistic noise model to analyze the error bounds of our system. The second on in-vivo pig data using an optical tracking system to provide a pseudo ground-truth. Accuracy results obtained were consistent with the synthetic experiments despite uncertainty introduced due to breathing motion, and remain inside acceptable error margin according to medical experts. Finally, a third experiment designed using data from pigs to simulate a real task of biopsy site relocalization, and evaluated by 10 GI experts. It clearly demonstrated the benefit of our system towards assisted guidance by improving the biopsy site retrieval rate from 47.5% to 94%. |
| Databáze: | OpenAIRE |
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