Low-Volume Contrast Medium Protocol for Comprehensive Cardiac and Aortoiliac CT Assessment in the Context of Transcatheter Aortic Valve Replacement

Autor: U. Joseph Schoepf, Lucas L. Geyer, Justin R. Silverman, Aleksander W. Krazinski, Daniel H. Steinberg, Fabian Bamberg, Carlo N. De Cecco
Rok vydání: 2015
Předmět:
Zdroj: Academic Radiology. 22:1138-1146
ISSN: 1076-6332
DOI: 10.1016/j.acra.2015.03.018
Popis: Rationale and Objectives To investigate the diagnostic performance of a comprehensive computed tomography (CT) protocol for both cardiac and aortoiliac evaluation of patients considered for transcatheter aortic valve replacement (TAVR) using a single, low-volume contrast medium (CM) injection. Materials and Methods Forty-four TAVR candidates were retrospectively analyzed. All underwent retrospectively electrocardiogram-gated cardiac CT followed by high-pitch CT angiography of the aortoiliac vasculature using one of two single injection protocols of 320 mgI/mL iodine CM: group A ( n = 22), iodine delivery rate-based (1.28 gI/s), 60-mL CM volume, 4.0 mL/s flow rate; group B ( n = 22), clinical routine protocol, 100-mL CM volume, 4.0 mL/s flow rate. Mean arterial attenuation, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were calculated. Subjective image quality was assessed. Results Aortic root and iliofemoral dimensions could be analyzed in all cases. Patient characteristics showed no significant differences. Mean attenuation at the levels of the aortic root (285.8 ± 83.0 HU vs 327.5 ± 70.8 HU, P = .080) and the iliofemoral access route (256.8 ± 88.5 HU vs 307.5 ± 93.2 HU, P = .071), as well as SNR and CNR were nonsignificantly lower in group A compared to group B. Subjective image quality was equivalent. Conclusions In multimorbid TAVR patients, the performance of a combined CT protocol using a single low-volume CM bolus is feasible with maintained image quality compared to a standard protocol.
Databáze: OpenAIRE