Long-term survival despite early loss of graft function after single lung transplantation for pulmonary fibrosis
| Autor: | J.W.K. van den Berg, W. van der Bij, J P Ouwens, W J de Boer, Gh Koeter |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Time Factors Adolescent Pulmonary Fibrosis Bronchiolitis obliterans Pulmonary function testing Idiopathic pulmonary fibrosis Postoperative Complications Fibrosis Forced Expiratory Volume Pulmonary fibrosis medicine Humans Radionuclide Imaging Bronchiolitis Obliterans Lung Transplantation business.industry Respiratory disease medicine.disease Surgery Respiratory Function Tests Radiography surgical procedures operative medicine.anatomical_structure Cardiology and Cardiovascular Medicine business Immunosuppressive Agents Lung Transplantation |
| Zdroj: | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 21(3) |
| ISSN: | 1053-2498 |
| Popis: | We report a patient who received a single, left lung transplantation for idiopathic pulmonary fibrosis. The effect of the graft on pulmonary improvement was only temporary, because the patient developed obliterative bronchiolitis (OB), resulting in complete destruction of the graft. The patient, however, remains alive 6 years after OB was diagnosed, apparently as a consequence of native lung improvement with triple-immunosuppressive medicine. This case is of interest for several reasons: first, it shows that pulmonary fibrosis may respond to intensive immunosuppressive therapy; second, it demonstrates that ventilation scintigraphy is useful in addition to pulmonary function tests in estimating the actual function of the graft after single lung transplantation; and third, it appears that the gradation of bronchiolitis obliterans syndrome (BOS) after single lung transplantation may overestimate the true function of the transplant. |
| Databáze: | OpenAIRE |
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