Morphofunctional Changes in the Kidneys in Chronic Endotoxemia against the Background of Hypothyroidism
| Autor: | A. I. Shchyogolev, S. A. Kalashnikova, G. A. Kovnatskaya |
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| Rok vydání: | 2012 |
| Předmět: |
Male
endocrine system medicine.medical_specialty endocrine system diseases Thyrotropin Physiology Enzyme-Linked Immunosorbent Assay Kidney General Biochemistry Genetics and Molecular Biology Hypothyroidism Internal medicine medicine Animals skin and connective tissue diseases business.industry Thyroid Kidney pathology Glomerulosclerosis General Medicine medicine.disease Endotoxemia Rats Thyroxine Endocrinology medicine.anatomical_structure Triiodothyronine sense organs business Hormone |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 153:516-518 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-012-1755-z |
| Popis: | We studied morphological structure of the kidneys in chronic endotoxemia modeled against the background of hypothyroidism. The detected changes did not differ from those under conditions of basic endotoxemia model and were characterized by the development of glomerulosclerosis and glomerulohyalinosis. The changes were less severe in rats with hypothyroidism and appeared at the late terms of the experiment. This indicated a moderate protective effect of preexisting thyroid hormone deficiency. |
| Databáze: | OpenAIRE |
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