Supplementary Materials and Methods, Table S1, Video legends, and Figure S1-5 from Reversal of Chemoresistance in Ovarian Cancer by Co-Delivery of a P-Glycoprotein Inhibitor and Paclitaxel in a Liposomal Platform

Autor: Ernst Lengyel, Vladimir Torchilin, Ed Luther, Hilary A. Kenny, Shravan Kumar Sriraman, Yilin Zhang
Rok vydání: 2023
DOI: 10.1158/1535-7163.22504032.v1
Popis: Table S1: Characterization of drug-loaded liposomes; Supplementary Figure S1: Liposome treatments reduced cell viability and inhibited cell migration; Supplementary Figure S2: Liposomes do not affect ovarian cancer cell adhesion/invasion in an organotypic 3 dimensional culture model; Supplement Figure S3: Tariquidar and paclitaxel co-loaded liposomes cause mitotic arrest in paclitaxel resistant cells; Supplementary Figure S4: Quantification of paclitaxel-mediated apoptotic events using laser scanning imaging cytometry; Supplementary Figure S5: Liposomal packaging of tariquidar does not affect metastatic growth in an orthotopic model of chemoresistant ovarian cancer.
Databáze: OpenAIRE