Neuronal outgrowth of PC-12 cells after combined treatment with nerve growth factor and a magnetic field: influence of the induced electric field strength
| Autor: | J. Schimmelpfeng, K. F. Weibezahn, H. Dertinger |
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| Rok vydání: | 2004 |
| Předmět: |
Materials science
Neurite Physiology Biophysics Flux Field strength Cell Enlargement Radiation Dosage Cell Line Nuclear magnetic resonance Electromagnetic Fields Electric field Nerve Growth Factor Neurites Animals Radiology Nuclear Medicine and imaging Bioelectromagnetics Neurons Dose-Response Relationship Drug Cell Differentiation Dose-Response Relationship Radiation General Medicine Drug Tolerance Magnetic field Rats Nerve growth factor Neuronal Outgrowth |
| Zdroj: | Bioelectromagnetics. 26(1) |
| ISSN: | 0197-8462 |
| Popis: | In view of possible therapeutic applications of magnetic fields, the effect of an enhancement of neuronal outgrowth at higher figures of flux density and induced field strength was investigated. On the average sinusoidal magnetic field treatment at 100 μTrms/50 Hz did not change nerve growth factor (NGF) induced neurite outgrowth to a statistically significant extent. These results suggest that further increasing the induced field strength by using either higher flux densities and/or more sophisticated wave forms might be necessary to cause the neuronal response of PC-12 cells, as seen in other experiments. Bioelectromagnetics 26:74–77, 2005. © 2004 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
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