Effects of dopamine and aminophylline on contrast-induced acute renal failure after coronary angioplasty in patients with preexisting renal insufficiency
Autor: | Kenneth M. Kent, Stefan Dosa, Martin B. Leon, Chester E. Clark, Margaret Harvey, Lowell F. Satler, Jeffrey J. Popma, Andrea Abizaid, Augusto D. Pichard, Gary S. Mintz |
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Rok vydání: | 1999 |
Předmět: |
Male
medicine.medical_specialty Cardiotonic Agents Dopamine medicine.medical_treatment Contrast Media Sodium Chloride law.invention Randomized controlled trial law Internal medicine Angioplasty medicine Humans Renal Insufficiency Angioplasty Balloon Coronary Saline Aged Chemotherapy business.industry Acute Kidney Injury medicine.disease Aminophylline Creatinine Anesthesia Cardiology Female Cardiology and Cardiovascular Medicine Complication business medicine.drug Kidney disease |
Zdroj: | The American Journal of Cardiology. 83:260-263 |
ISSN: | 0002-9149 |
DOI: | 10.1016/s0002-9149(98)00833-9 |
Popis: | In phase 1 of this study, 60 patients undergoing coronary angioplasty were randomized to receive saline, dopamine, or aminophylline; the overall incidence of contrast-induced renal failure was 38%, without difference among the 3 groups. In phase 2 of this study, 72 patients with established contrast-induced renal failure were randomized to receive saline or dopamine; dopamine had a deleterious effect on the severity of renal failure, prolonging the course. |
Databáze: | OpenAIRE |
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