Effects of dopamine and aminophylline on contrast-induced acute renal failure after coronary angioplasty in patients with preexisting renal insufficiency

Autor: Kenneth M. Kent, Stefan Dosa, Martin B. Leon, Chester E. Clark, Margaret Harvey, Lowell F. Satler, Jeffrey J. Popma, Andrea Abizaid, Augusto D. Pichard, Gary S. Mintz
Rok vydání: 1999
Předmět:
Zdroj: The American Journal of Cardiology. 83:260-263
ISSN: 0002-9149
DOI: 10.1016/s0002-9149(98)00833-9
Popis: In phase 1 of this study, 60 patients undergoing coronary angioplasty were randomized to receive saline, dopamine, or aminophylline; the overall incidence of contrast-induced renal failure was 38%, without difference among the 3 groups. In phase 2 of this study, 72 patients with established contrast-induced renal failure were randomized to receive saline or dopamine; dopamine had a deleterious effect on the severity of renal failure, prolonging the course.
Databáze: OpenAIRE