Drug induced hypofibrinolysis: A cause of venous thrombosis
| Autor: | Howard V. Hufnagel, Michael D. Sulkin, Alfred S. Gervin, Kenneth G. Mason |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Drug
medicine.medical_specialty media_common.quotation_subject Femoral vein Thrombophlebitis Fibrin Potassium Chloride Persistence (computer science) Dogs Glucose Solution Hypertonic Cephalothin medicine Animals Humans Infusions Parenteral Diatrizoate Meglumine media_common biology business.industry Fibrinolysis Incidence (epidemiology) Blood Coagulation Disorders Hydrogen-Ion Concentration medicine.disease Surgery Venous thrombosis Anesthesia biology.protein Etiology business |
| Zdroj: | Journal of Surgical Research. 19:233-238 |
| ISSN: | 0022-4804 |
| DOI: | 10.1016/0022-4804(75)90086-4 |
| Popis: | Three medications clinically associated with thrombophlebitis when administered intravenously markedly reduced fibrinolytic activity in canine femoral vein. A fourth medication with no associated incidence of thrombophlebitis had no effect on fibrinolytic activity. Drug-induced decreases in vascular fibrinolytic activity may be significant in the etiology of postinfusion thrombophlebitis by allowing persistence and propagation of small fibrin thrombi. |
| Databáze: | OpenAIRE |
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