Dopamine inhibition and the adaptation of behavior to ongoing reality
| Autor: | Klemens Gutbrod, U. Baas, Hans Pihan, Armin Schnider |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Male
Confabulation Dopamine Prefrontal Cortex Neural Pathways medicine Limbic System Humans Memory disorder Cerebral Hemorrhage Behavior Memory Disorders Dose-Response Relationship Drug General Neuroscience Memoria Dopaminergic Cognitive disorder Dopamine antagonist Neural Inhibition Recovery of Function medicine.disease Risperidone Adaptation Physiological Treatment Outcome Dopamine Antagonists Disconnection medicine.symptom Psychology Tomography X-Ray Computed Cognitive psychology medicine.drug |
| Zdroj: | Neuroreport. 15(4) |
| ISSN: | 0959-4965 |
| Popis: | Spontaneous confabulation is a rare memory disorder resulting from orbitofrontal damage or disconnection. Patients act on the basis of memories that do not pertain to the current situation, and are disoriented. No medical treatment is known. Recent studies suggest that subcortical dopaminergic structures are involved in the selection of currently relevant memories. We present a patient who regained the ability to adapt thought and behavior to ongoing reality when treated with risperidone, a dopamine antagonist. |
| Databáze: | OpenAIRE |
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