Concomitant confluent and reticulated papillomatosis and acanthosis nigricans in an obese girl with insulin resistance successfully treated with oral minocycline: Case report and published work review
| Autor: | Masanobu Sakaguchi, Takeshi Fukumoto, Takeshi Kozaru, Masahiro Oka |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Skin Neoplasms Biopsy Minocycline Dermatology 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound Rare Diseases 0302 clinical medicine Insulin resistance Internal medicine medicine Confluent and reticulated papillomatosis Humans Acanthosis Nigricans Obesity Child Acanthosis nigricans Skin C-Peptide Papilloma medicine.diagnostic_test C-peptide business.industry Syndrome General Medicine Alkaline Phosphatase medicine.disease Anti-Bacterial Agents Treatment Outcome Endocrinology chemistry 030220 oncology & carcinogenesis Concomitant Female Insulin Resistance business medicine.drug |
| Zdroj: | The Journal of Dermatology. 44:954-958 |
| ISSN: | 0385-2407 |
| DOI: | 10.1111/1346-8138.13819 |
| Popis: | Concomitant confluent and reticulated papillomatosis (CRP) and acanthosis nigricans (AN) is rare. We present a case of concomitant CRP and obesity-associated AN in a 12-year-old obese Japanese girl. Curiously, oral minocycline therapy, which has been shown to be effective for CRP, was effective against both CRP and AN. Possible mechanisms by which minocycline could have improved skin lesions of CRP and obesity-associated AN are discussed. In addition, reports of concomitant CRP and obesity-associated AN are reviewed. CRP and obesity-associated AN share common clinicopathological features and some reports have described concomitant CRP and obesity-associated AN. Together with the observation that skin lesions of CRP and obesity-associated AN in the present case responded to oral minocycline therapy, these facts suggest a tight relationship or a common pathogenetic pathway between these pathologies. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text