Geographic dispersal and genetic diversity of tick-borne phleboviruses (Phenuiviridae, Phlebovirus) as revealed by the analysis of L segment sequences
| Autor: | Daniel Bravo-Barriga, Maria Luísa Vieira, Victor Pimentel, Maria das Neves Paiva-Cardoso, Mónica Nunes, André Pereira, Ana B. Abecasis, Manuel Bueno Martinez, Rita Afonso, Ricardo Parreira, Carla Maia, Eva Frontera, Ferdinando B. Freitas |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Nymph
Phlebovirus 0301 basic medicine Most recent common ancestor Rhipicephalus sanguineus 030231 tropical medicine Zoology Microbiology 03 medical and health sciences Spatio-Temporal Analysis 0302 clinical medicine Sensu parasitic diseases Animals RNA Viruses Phylogeny Ovum Genetic diversity Geography Portugal biology Phylogenetic tree Genetic Variation Sequence Analysis DNA biology.organism_classification Infectious Disease Transmission Vertical Phylogeography 030104 developmental biology Infectious Diseases Spain Insect Science RNA Viral Biological dispersal Parasitology |
| Zdroj: | Ticks and Tick-borne Diseases. 10:942-948 |
| ISSN: | 1877-959X |
| Popis: | The large diversity of new tick-borne phleboviruses, and the negative impacts of the virulent viruses on human/animal health have led to a growing interest in their analysis. In this report, new insights are brought out into the diversity of putative phleboviruses circulating in Portugal (both the continental territory and the islands of Sao Miguel, in the Azores, and Madeira), as well as in the Spanish western regions of Extremadura and Castilla and Leon. Phlebovirus sequences were frequently detected (L-segment) from both questing and feeding ticks, but especially in Rhipicephalus sanguineus sensu lato (s.l.) specimens. These sequences were detected in adult ticks, as well as nymphs and eggs, supporting the hypothesis of viral maintenance by vertical transmission. Though multiple genetic groups could be identified in phylogenetic trees (AnLuc, KarMa, RiPar virus 1, and Spanish group 1 and 2), all the sequences from Portugal and Spain shared common ancestry with other viral sequence obtained from samples collected over a large geographic coverage. Spatiotemporal analysis placed Middle-East as the geographic origin of the most recent common ancestor (MRCA) of all phleboviruses analysed in the present study. More recent viral transitions might include migrations from Spain to continental Portugal, and from there to the Portuguese Islands. Our findings suggest that the time of the MRCA of phleboviruses was dated around 225 years ago [95% HPD: 124–387 year before the last sampling date]. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect