Selectivity of Calcium Antagonism and Serotonin Antagonism with Respect to Venous and Arterial Tissues
Autor: | Paul M. Vanhoutte, J.M. Van Nueten |
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Rok vydání: | 1981 |
Předmět: |
0301 basic medicine
Serotonin medicine.medical_specialty Ketanserin Cinnarizine chemistry.chemical_element 030204 cardiovascular system & hematology Calcium Muscle Smooth Vascular Veins 03 medical and health sciences Dogs 0302 clinical medicine Piperidines Internal medicine medicine Animals Serotonin Antagonists Flunarizine business.industry Arteries Rats 030104 developmental biology Endocrinology chemistry Rabbits medicine.symptom Cardiology and Cardiovascular Medicine business Antagonism Muscle Contraction Muscle contraction medicine.drug |
Zdroj: | Angiology. 32:476-484 |
ISSN: | 1940-1574 0003-3197 |
DOI: | 10.1177/000331978103200704 |
Popis: | There are marked differences in responsiveness to naturally occurring vasoactive substances1-4 between isolated blood vessels of different anatomical origin and in particular between arteries and veins. This discussion will deal with two major aspects where arterial and venous smooth muscle differ in their sensitivity to vasoactive agents; their sensitivity to inhibitors of calcium-influx (Ca2+ antagonists) on the one hand and their reactivity to serotonin (5-hydroxytryptamine) and serotonin antagonists, on the other. |
Databáze: | OpenAIRE |
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