White-coat and masked hypertension are associated with albuminuria in a general population: the Hisayama Study

Autor: Toshiharu Ninomiya, Koji Yonemoto, Naoko Mukai, Yoichiro Hirakawa, Masayo Fukuhara, Yutaka Kiyohara, Satoko Sakata, Takanari Kitazono, Hisatomi Arima, Jun Hata
Rok vydání: 2017
Předmět:
Zdroj: Hypertension research : official journal of the Japanese Society of Hypertension. 40(11)
ISSN: 1348-4214
Popis: Epidemiological and clinical studies have investigated the influence of hypertension on chronic kidney disease (CKD), but limited data are available for the associations of white-coat hypertension (WCHT), masked hypertension (MHT) and sustained hypertension (SHT) with kidney dysfunction in general populations. We examined the associations of these types of hypertension with CKD (albuminuria and reduction in estimated glomerular filtration rate (eGFR)) in a cross-sectional survey of 2974 community-dwelling Japanese aged ⩾40 years. The types of hypertension were defined based on combined measurements of clinic and home blood pressures. Albuminuria was determined as urinary albumin–creatinine ratio (UACR) levels ⩾30.0 mg g−1. The eGFR was calculated using the Japanese equation. The age- and sex-adjusted geometric mean of the UACR values was significantly higher in the subjects with WCHT (20.2 mg g−1), MHT (19.6 mg g−1) and SHT (31.6 mg g−1) than in those with normotension (NT) (12.5 mg g−1) (all P
Databáze: OpenAIRE