Intact Organization of Tactile Space Perception in Isolated Focal Dystonia

Autor: Tina Mainka, Matthew R. Longo, Tobias Bäumer, Arne Knutzen, Wolf-Julian Neumann, Elena Azañón, Andrea A. Kühn, Kirsten E. Zeuner, Friederike Borngräber, Christos Ganos
Rok vydání: 2020
Předmět:
somatosensation
0301 basic medicine
Adult
tactile distance perception
congenital
hereditary
and neonatal diseases and abnormalities
medicine.medical_specialty
Movement disorders
cervical dystonia
somatosensory receptive fields
media_common.quotation_subject
Blepharospasm
blepharospasm
Somatosensory system
focal dystonia
03 medical and health sciences
0302 clinical medicine
Physical medicine and rehabilitation
Perception
medicine
Humans
Cervical dystonia
media_common
business.industry
Focal dystonia
medicine.disease
Hand
030104 developmental biology
medicine.anatomical_structure
Neurology
Touch Perception
Dystonic Disorders
Touch
Space Perception
Forehead
Neurology (clinical)
medicine.symptom
business
600 Technik
Medizin
angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
030217 neurology & neurosurgery
Meige Syndrome
Zdroj: Movement disorders, 36(8):1949-1955
ISSN: 1531-8257
Popis: BACKGROUND Systematic perceptual distortions of tactile space have been documented in healthy adults. In isolated focal dystonia impaired spatial somatosensory processing is suggested to be a central pathophysiological finding, but the structure of tactile space for different body parts has not been previously explored. OBJECTIVES The objective of this study was to assess tactile space organization with a novel behavioral paradigm of tactile distance perception in patients with isolated focal dystonia and controls. METHODS Three groups of isolated focal dystonia patients (cervical dystonia, blepharospasm/Meige syndrome, focal hand dystonia) and controls estimated perceived distances between 2 touches across 8 orientations on the back of both hands and the forehead. RESULTS Stimulus size judgments differed significantly across orientations in all groups replicating distortions of tactile space known for healthy individuals. There were no differences between groups in the behavioral parameters we assessed on the hands and forehead. CONCLUSIONS Tactile space organization is comparable between patients with isolated focal dystonia and healthy controls in dystonic and unaffected body parts. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Databáze: OpenAIRE
Externí odkaz: