Photoresponsive cross-linked polymeric particles for phototriggered burst release
| Autor: | Peng Wang, Xinjing Tang, LiLi Yu, Cong Lv, Yedong Chen, Zhen Wang |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Cell Survival
Ultraviolet Rays Photochemistry Biochemistry Fluorescence spectroscopy Cell Line Polymerization chemistry.chemical_compound Mice Oxazines Animals Physical and Theoretical Chemistry Particle Size Nitrobenzenes Fluorescent Dyes Ethanol Chemistry Macrophages Nile red Biological Transport General Medicine Fluoresceins Fluorescence Miniemulsion Monomer Spectrometry Fluorescence Microscopy Electron Scanning Particle Methacrylates Nanoparticles Emulsions Particle size |
| Zdroj: | Photochemistry and photobiology. 89(3) |
| ISSN: | 1751-1097 |
| Popis: | We synthesized a series of cross-linked photoresponsive polymeric particles with photolabile monomers and cross-linkers through miniemulsion polymerization. These particles are quite stable in dark, while light irradiation caused the breakage of particles and the efficient release of encapsulated contents up to 95% based on Nile red fluorescence. Photoswitches of particle systems were confirmed by fluorescence spectroscopy, SEM and colorimetry. Particle uptake and triggered release in RAW264.7 cells were confirmed by fluorescein diacetate loaded particles. |
| Databáze: | OpenAIRE |
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