Secondary bloodstream infection in critically ill patients with COVID-19
| Autor: | Junli Zhang, Peng Lan, Jun Yi, Changming Yang, Xiaoyan Gong, Huiqing Ge, Xiaoling Xu, Limin Liu, Jiancang Zhou, Fangfang Lv |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Medicine (General) Coronavirus disease 2019 Coinfection SARS-CoV-2 Critical Illness Biochemistry (medical) COVID-19 Cell Biology General Medicine secondary bloodstream infection extracorporeal membrane oxygenation Biochemistry Intensive Care Units R5-920 risk factor Sepsis Humans secondary pneumonia Retrospective Clinical Research Report |
| Zdroj: | The Journal of International Medical Research Journal of International Medical Research, Vol 49 (2021) |
| ISSN: | 1473-2300 0300-0605 |
| Popis: | Objective Secondary infection, especially bloodstream infection, is an important cause of death in critically ill patients with COVID-19. We aimed to describe secondary bloodstream infection (SBI) in critically ill adults with COVID-19 in the intensive care unit (ICU) and to explore risk factors related to SBI. Methods We reviewed all SBI cases among critically ill patients with COVID-19 from 12 February 2020 to 24 March 2020 in the COVID-19 ICU of Jingmen First People's Hospital. We compared risk factors associated with bloodstream infection in this study. All SBIs were confirmed by blood culture. Results We identified five cases of SBI among the 32 patients: three with Enterococcus faecium, one mixed septicemia ( E. faecium and Candida albicans), and one C. parapsilosis. There were no significant differences between the SBI group and non-SBI group. Significant risk factors for SBI were extracorporeal membrane oxygenation, central venous catheter, indwelling urethral catheter, and nasogastric tube. Conclusions Our findings confirmed that the incidence of secondary infection, particularly SBI, and mortality are high among critically ill patients with COVID-19. We showed that long-term hospitalization and invasive procedures such as tracheotomy, central venous catheter, indwelling urethral catheter, and nasogastric tube are risk factors for SBI and other complications. |
| Databáze: | OpenAIRE |
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