Movie 7 from Metabolic Screening of Cytotoxic T-cell Effector Function Reveals the Role of CRAC Channels in Regulating Lethal Hit Delivery

Autor: Peter Friedl, Bettina Weigelin, Carl G. Figdor, Jeroen A. van der Laak, Tonke K. Raaijmakers, Louis Wolf, Esther Wagena, Cindy E. Dieteren, Jeroen Slaats
Rok vydání: 2023
DOI: 10.1158/2326-6066.22544277.v1
Popis: Single CTL-associated MEC1/OVA Ca2+ event followed by target cell death in control culture (DMSO) and lack of CTL-associated MEC1/OVA Ca2+ events despite stable CTL-target cell interactions in the presence of BTP2. Arrowhead highlights the CTL-associated MEC1/OVA Ca2+ event. Time stamp, h:min. Fire LUT, Ca2+ intensity. Scale bar, 10 µm.
Databáze: OpenAIRE