Movie 7 from Metabolic Screening of Cytotoxic T-cell Effector Function Reveals the Role of CRAC Channels in Regulating Lethal Hit Delivery
Autor: | Peter Friedl, Bettina Weigelin, Carl G. Figdor, Jeroen A. van der Laak, Tonke K. Raaijmakers, Louis Wolf, Esther Wagena, Cindy E. Dieteren, Jeroen Slaats |
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Rok vydání: | 2023 |
DOI: | 10.1158/2326-6066.22544277.v1 |
Popis: | Single CTL-associated MEC1/OVA Ca2+ event followed by target cell death in control culture (DMSO) and lack of CTL-associated MEC1/OVA Ca2+ events despite stable CTL-target cell interactions in the presence of BTP2. Arrowhead highlights the CTL-associated MEC1/OVA Ca2+ event. Time stamp, h:min. Fire LUT, Ca2+ intensity. Scale bar, 10 µm. |
Databáze: | OpenAIRE |
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