Multidisciplinary Management of the Adverse Effects of Apremilast
| Autor: | E. Trujillo Martín, M.D. Martín-Arranz, J. Alonso Suárez, M.C. Herrero Manso, M.A. Rodríguez-Sagrado, E. Daudén Tello, A. García-Merino, J. Rosas Gómez de Salazar, I. Marín-Jiménez, J. Porta Etessam, C. Blasco Maldonado, A. Jiménez Morales, E. Beltrán Catalán, L. Salgado-Boquete |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Diarrhea medicine.medical_specialty Histology Nausea Dermatology Náuseas Multidisciplinary team Pathology and Forensic Medicine Pharmacological treatment 03 medical and health sciences 0302 clinical medicine Multidisciplinary approach Medicine Humans Psoriasis Apremilast Adverse effect Intensive care medicine Patient Care Team business.industry Adverse effects Headache Disease Management Combined Modality Therapy Discontinuation Thalidomide Efectos adversos 030104 developmental biology Practice Guidelines as Topic Cefalea Phosphodiesterase 4 Inhibitors medicine.symptom Diarrea business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Actas Dermo-Sifiliograficas r-FISABIO. Repositorio Institucional de Producción Científica instname r-FISABIO: Repositorio Institucional de Producción Científica Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO) |
| ISSN: | 2173-5778 0001-7310 |
| Popis: | We present a series of general and specific recommendations based on pathophysiologic considerations for managing the most common adverse effects of apremilast that lead to treatment discontinuation: diarrhea, nausea, and headache. The recommendations are based on a review of the literature and the experience of a multidisciplinary team of 14 experts including dermatologists, rheumatologists, neurologists, gastroenterologists, pharmacists, and nurses. We propose a series of simple algorithms that include clinical actions and suggestions for pharmacologic treatment. The adverse effects of apremilast can be managed from a multidisciplinary approach. The purpose of optimizing management is to bring clinical benefits to patients. (C) 2020 AEDV. Published by Elsevier Espana, S.L.U. This is an open access article under the CC BY-NC-ND license |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect