Serum homocysteine concentration as a marker of nutritional status of healthy subjects in Crete, Greece
| Autor: | N. Malliaraki, E. S. Ganotakis, G. E. Vrentzos, E. G. Petinellis, A. Repa, J. A. Papadakis, D. E. Bampalis, V. Lemonomichelaki |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Homocysteine Mediterranean diet Population Medicine (miscellaneous) Physiology Nutritional Status Rural Health Diet Mediterranean chemistry.chemical_compound Folic Acid Risk Factors medicine Humans Vitamin B12 education Aged chemistry.chemical_classification Creatinine education.field_of_study Nutrition and Dietetics medicine.diagnostic_test Greece business.industry Feeding Behavior Middle Aged medicine.disease Atherosclerosis Obesity Diet Records Surgery chemistry Vitamin B Complex Female Lipid profile business Biomarkers Polyunsaturated fatty acid |
| Zdroj: | Journal of human nutrition and dietetics : the official journal of the British Dietetic Association. 19(2) |
| ISSN: | 0952-3871 |
| Popis: | Background Dietary habits are an important determinant of serum homocysteine (tHcy), which may be a marker rather than a cause of progression of the atherosclerotic process. The aim of the present study was to evaluate the nutritional status, and to determine the serum tHcy concentrations in healthy subjects who live in rural areas of Crete, and who theoretically follow a contemporary Mediterranean-style diet. Methods Serum tHcy, folate, vitamin B12, creatinine, glucose, and the lipid profile, were measured in 203 (141 men and 62 women) healthy subjects, aged 33–78 years. The major risk factors for cardiovascular disease such as age, gender, cigarette smoking, obesity were recorded and dietary data were assessed using a 3-day weighed food intake record. Results Our population had high serum tHcy, low serum folate concentrations and lower than the traditional Cretan dietary folate intake [median (range): 12.0 (3.6–44.7) μmol L−1, 7.9 (1.9–15.5) ng mL−1 and 241 (68–1106) μg, respectively]. Dietary intake of fibre, omega-3, and mono- or/ polyunsaturated fatty acids was also low. An inverse relation was observed between serum tHcy concentrations and serum folate (r = −0.28; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text