Longitudinal change in health-related quality of life in people with prevalent and incident type 2 diabetes compared to diabetes-free controls
| Autor: | M Schunk, Saskia Hartwig, Christa Scheidt-Nave, Henry Völzke, Teresa Tamayo, Rolf Holle, Ina-Maria Rückert-Eheberg, Christa Meisinger, Annette Peters, Sabine Schipf, Peter Reitmeir, Ute Ellert, Alexander Kluttig |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Research design
Male Obesity Type 2 diabetes Diabetes mellitus Cohort studies Germany Longitudinal studies Mental health and psychiatry Myocardial infarction Physiology Myocardial Infarction lcsh:Medicine Cohort Studies Geographical Locations 0302 clinical medicine Endocrinology Quality of life Medicine and Health Sciences Prevalence Medicine 030212 general & internal medicine Longitudinal Studies lcsh:Science education.field_of_study Multidisciplinary Incidence (epidemiology) Incidence Age Factors Middle Aged humanities Type 2 Diabetes Europe Physiological Parameters Research Design Female Cohort study Research Article Endocrine Disorders Population Cardiology 030209 endocrinology & metabolism Research and Analysis Methods 03 medical and health sciences Sex Factors Mental Health and Psychiatry Diabetes Mellitus Humans ddc:610 education Aged business.industry lcsh:R Body Weight Biology and Life Sciences medicine.disease Diabetes Mellitus Type 2 Metabolic Disorders Case-Control Studies People and Places Quality of Life lcsh:Q business Demography |
| Zdroj: | PLOS ONE, 12(5):e0176895 PLoS ONE PLoS ONE 12:e0176895 (2017) PLoS ONE, Vol 12, Iss 5, p e0176895 (2017) |
| Popis: | Objective The objective of this analysis is to compare people with prevalent type 2 diabetes, incident type 2 diabetes and without diabetes with respect to longitudinal change in health-related quality of life (HRQOL) when adjusting for baseline determinants of HRQOL. Research design and methods Primary baseline and follow-up data from three regional and one national population-based cohort studies in Germany were pooled for analysis. HRQOL was measured using physical and mental health summary scores (PCS and MCS) from the German version of the Short Form Health Survey with 36 or 12 items. Mean score change per observation year was compared between the three groups (prevalent diabetes, incident diabetes, no diabetes) based on linear regression models. Results The analysis included pooled data from 5367 people aged 45–74 years at baseline. Of these, 85.5% reported no diabetes at baseline and follow-up, 6.3% reported diabetes at both baseline and follow-up (prevalent diabetes), and 8.2% reported diabetes only at follow-up (incident diabetes). Over a mean observation period of 8.7 years, annual decline in HRQOL scores is pronounced at 0.27–0.32 (PCS) and 0.34–0.38 (MCS) in the group with prevalent diabetes compared with people without diabetes. Those with incident diabetes showed intermediate values but did not differ significantly from people without diabetes after adjustment for covariates in the full model. Conclusion Compared with data from cross-sectional analysis, the HRQOL loss associated with prevalent diabetes appears to be much larger than previously assumed. |
| Databáze: | OpenAIRE |
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