Impact of atrial arrhythmias on outcome in adults with congenital heart disease
| Autor: | B.J.M. Mulder, G.Tj. Sieswerda, Joey M. Kuijpers, B.J. Bouma, A.P.J. van Dijk, H. Yang, T.C. Konings, J. R. de Groot, Martijn C. Post |
|---|---|
| Přispěvatelé: | Cardiology, ACS - Heart failure & arrhythmias, Graduate School, ACS - Amsterdam Cardiovascular Sciences, APH - Personalized Medicine, APH - Aging & Later Life, ACS - Pulmonary hypertension & thrombosis |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Heart Defects Congenital Male medicine.medical_specialty Heart disease Vascular damage Radboud Institute for Health Sciences [Radboudumc 16] 030204 cardiovascular system & hematology 03 medical and health sciences Young Adult 0302 clinical medicine All institutes and research themes of the Radboud University Medical Center Interquartile range Risk Factors Internal medicine Atrial Fibrillation medicine Humans 030212 general & internal medicine Prospective Studies Mortality Prospective cohort study Stroke Aged Aged 80 and over Heart Failure business.industry Hazard ratio Atrial fibrillation Middle Aged medicine.disease Treatment Outcome Heart failure Cardiology Female Cardiology and Cardiovascular Medicine business Atrial flutter Follow-Up Studies |
| Zdroj: | Yang, H, Kuijpers, M J E, de Groot, J R, Konings, T C, van Dijk, A, Sieswerda, G T, Post, M C, Mulder, B J M & Bouma, B J 2017, ' Impact of atrial arrhythmias on outcome in adults with congenital heart disease ', International Journal of Cardiology, vol. 248, pp. 152-154 . https://doi.org/10.1016/j.ijcard.2017.06.073 International Journal of Cardiology, 248, pp. 152-154 International Journal of Cardiology, 248, 152-154 International Journal of Cardiology, 248, 152-154. Elsevier Ireland Ltd International journal of cardiology, 248, 152-154. Elsevier Ireland Ltd |
| ISSN: | 0167-5273 |
| DOI: | 10.1016/j.ijcard.2017.06.073 |
| Popis: | Background: Adults with congenital heart disease (ACHD) are affected by atrial arrhythmias (AA). To elucidate the impact of AA on prognosis, we aimed to determine the impact of AA on death, heart failure and stroke in ACHD patients in a prospective nationwide clinical registry. Methods: All patients aged >= 18 years included in the CONCOR registry per October 1st 2015 were analysed. Prior AA was defined as atrial fibrillation, atrial flutter or unspecified AA before inclusion in CONCOR and new-onset AA as a first documented AA during follow-up. The outcomes were death, first stroke and first admission for heart failure (HF). Results: The study cohort comprised 14,224 patients (baseline median age 33.6 [IQR 23-47], male 49.5%, AA n = 1501, complex defect 10.3%, repaired defect 58.9%). Median follow-up was 6.5 years [IQR 3-10]. Adjusting for age, sex, repair status and defect severity, patients with prior AA had higher mortality and more HF admissions, but no increased risk of stroke compared to those without AA (HR = 2.11; 95% CI = 1.79-2.49; p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect