Narrowing the spectrum: the new frontier of precision antimicrobials
| Autor: | Caitlin N. Spaulding, Karen W. Dodson, Alexandra E. Paharik, Scott J. Hultgren, Henry L. Schreiber |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Standard of care lcsh:QH426-470 medicine.drug_class Antibiotics lcsh:Medicine 030230 surgery 03 medical and health sciences 0302 clinical medicine Antibiotic resistance Anti-Infective Agents Genetics medicine Animals Humans Precision Medicine Intensive care medicine Molecular Biology Genetics (clinical) business.industry Comment lcsh:R Bacterial Infections Antimicrobial Gastrointestinal Microbiome 3. Good health lcsh:Genetics 030104 developmental biology Molecular Medicine business |
| Zdroj: | Genome Medicine, Vol 9, Iss 1, Pp 1-4 (2017) Genome Medicine |
| DOI: | 10.1186/s13073-017-0504-3 |
| Popis: | Editorial summary Antibiotics have become the standard of care for bacterial infections. However, rising rates of antibiotic-resistant infections are outpacing the development of new antimicrobials. Broad-spectrum antibiotics also harm beneficial microbial communities inhabiting humans. To combat antibiotic resistance and protect these communities, new precision antimicrobials must be engineered to target specific pathogens. |
| Databáze: | OpenAIRE |
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