Liquid tissue surrogates for X-ray and CT phantom studies
| Autor: | Benjamin M. Yeh, Peter J. Bonitatibus, Robert Edgar Colborn, Peter Michael Edic, Jack W. Lambert, Paul Fitzgerald |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Elemental composition
business.industry Chemistry Phantoms Imaging X-ray Adipose tissue Soft tissue General Medicine Imaging phantom Article 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Hounsfield scale Attenuation coefficient Image Processing Computer-Assisted Phantom studies Nuclear medicine business Tomography X-Ray Computed |
| Zdroj: | Medical physics. 44(12) |
| ISSN: | 2473-4209 |
| Popis: | Purpose To develop a simple method for producing liquid-tissue-surrogate (LTS) materials that accurately represent human soft tissues in terms of density and X-ray attenuation coefficient. Methods and Materials We evaluated hypothetical mixtures of water, glycerol, butanol, methanol, sodium chloride, and potassium nitrate; these mixtures were intended to emulate human adipose, blood, brain, kidney, liver, muscle, pancreas, and skin. We compared the hypothetical densities, effective atomic numbers (Zeff), and calculated discrete-energy CT attenuation (Hounsfield Units (HU)) of the proposed materials with those of human tissue elemental composition as specified in International Commission on Radiation Units (ICRU) Report 46. We then physically formulated the proposed LTS materials for adipose, liver, and pancreas tissue, and measured the polyenergetic CT attenuation (also expressed as HU) of these materials within a 32-cm phantom using a 64-slice clinical CT scanner at 80 kVp, 100 kVp, 120 kVp, and 140 kVp. Results The predicted densities, Zeff, and calculated discrete-energy CT attenuation of our proposed formulations generally agreed with those of ICRU within |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text