A comparison of the survival and implantation rates of blastocysts that were vitrified on post-fertilization day five, six and seven
| Autor: | Kuspinar Goktan, Avci Berrin, Saribal Seda, Kasapoglu Isıl, Uncu Gurkan, Ata Baris |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pregnancy Rate
Clinical pregnancy 030209 endocrinology & metabolism Fertilization in Vitro Cryopreservation Embryo Culture Techniques Andrology 03 medical and health sciences 0302 clinical medicine Human fertilization Pregnancy Ongoing pregnancy Humans Medicine Inner cell mass Embryo Implantation Blastocyst reproductive and urinary physiology Retrospective Studies 030219 obstetrics & reproductive medicine urogenital system business.industry Obstetrics and Gynecology Retrospective cohort study Embryo General Medicine Embryo Transfer Vitrification medicine.anatomical_structure Reproductive Medicine embryonic structures Female business |
| Zdroj: | Human Fertility. 22:204-211 |
| ISSN: | 1742-8149 1464-7273 |
| DOI: | 10.1080/14647273.2018.1468091 |
| Popis: | The goal of this retrospective cohort study was to compare survival, implantation, clinical and ongoing pregnancy rates between blastocysts that were vitrified on post-fertilization days 5, 6 and 7. Before vitrification, blastocysts were evaluated in terms of morphology and blastocyst expansion, inner cell mass and trophectoderm quality. They were thawed and transfered in a subsequent artificial cycle. Embryo implantation rates were 39%, 25% and 25% for blastocysts that were vitrified on days 5, 6, and 7, respectively (p = 0.006). Clinical and ongoing pregnancy rates were 19%, 12%, 13% (p = 0.100) and 9%, 7%, 12% (p = 0.99) for days 5, 6 and 7 blastocysts, respectively. Day 5 blastocysts had significantly higher full-collapsing score after assisted-hatching compared to days 6 and 7 blastocysts (p = 0.014). As blastocyst quality increased, implantation and clinical pregnancy rates increased in all groups and both parameters were statistically significantly higher on day 5 blastocysts than on days 6 or 7 (p = 0.001). It was clearly found that good quality blastocysts obtained on day 5 have higher implantation and clinical pregnancy rates than 6th and 7th day cryopreserved embryos. There were no statistically significant differences between the cryopreserved embryos on days 6 and 7 regarding the implantation, clinic and ongoing pregnancy rates. |
| Databáze: | OpenAIRE |
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