| Autor: |
Shoji OGAWA, Tamaki YANA, Tomohiro KONDO, Toshiya OKADA |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
The Journal of veterinary medical science. 84(9) |
| ISSN: |
1347-7439 |
| Popis: |
Changes in body weight (BW), systolic blood pressure (SBP), and localization of renin in the kidneys of neonates born to normal mothers (C neonates) or to five-sixths (5/6) nephrectomized (2/3 left kidney and right kidney) mothers (Nx neonates) were studied. Maternal 5/6 nephrectomy caused weight loss in neonates but no differences in SBP or renin localization. Culling Nx neonates to a litter of 3 at 1 day after birth resulted in growth catching up with C neonates from 3 weeks old and increases in both SBP and renin-positive cells in neonatal kidney. These findings revealed that maternal 5/6 nephrectomy results in low-birth-weight neonates and that these neonates are at increased risk of metabolic syndrome by catch-up growth. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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