IMMUNOLOGICAL CROSS-REACTION BETWEEN ANTIGEN Tp-4 OF TREPONEMA PALLIDUM AND AN ANTIGEN COMMON TO A WIDE RANGE OF BACTERIA
| Autor: | Niels Høiby, Carsten Sand Petersen, Nils Strandberg Pedersen, Nils H. Axelsen, Peter Hindersson |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Antigens
Bacterial Treponema General Immunology and Microbiology Pseudomonas aeruginosa Cross reactions General Medicine Cross Reactions Biology urologic and male genital diseases medicine.disease medicine.disease_cause biology.organism_classification Microbiology Virology Epitopes Species Specificity Antigen Immunity medicine Syphilis Treponema pallidum Reiter treponeme Immunoelectrophoresis Bacteria |
| Zdroj: | Acta Pathologica Microbiologica Scandinavica Series B: Microbiology. :183-188 |
| ISSN: | 0108-0180 |
| DOI: | 10.1111/j.1699-0463.1984.tb02818.x |
| Popis: | By electro-immunoprecipitation methods it was shown that antigen Tp-4 of Treponema pallidum, antigen TR-c of the Reiter treponeme and 'Common Antigen' of Pseudomonas aeruginosa are immunologically cross-reactive. This finding establishes a taxonomic relationship between T. pallidum and a wide range of bacteria. The cross-reactivity explains some false positive reactions in serodiagnostic treponemal tests for syphilis. The cross-reactivity may also play a role in a possible 'normal' immunity against infection with T. pallidum induced by antigens by the normal human bacterial flora. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|