Antifungal activity of essential oil from Mentha spicata L. and Mentha pulegium L. growing wild in Sardinia island (Italy)
| Autor: | Carlos Cavaleiro, Mj. Gonçalves, Silvia Porcedda, D Falconieri, Alessandra Piras, Lígia Salgueiro, Andrea Maxia |
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| Rok vydání: | 2019 |
| Předmět: |
Antifungal
Mentha spicata Traditional medicine 010405 organic chemistry medicine.drug_class Organic Chemistry Virulence Plant Science Biology biology.organism_classification 01 natural sciences Biochemistry humanities food.food 0104 chemical sciences Analytical Chemistry law.invention 010404 medicinal & biomolecular chemistry food law medicine Mentha pulegium Candida albicans Essential oil |
| Zdroj: | Natural Product Research. 35:993-999 |
| ISSN: | 1478-6427 1478-6419 |
| DOI: | 10.1080/14786419.2019.1610755 |
| Popis: | This study aims to evaluate the antifungal activity of Mentha spicata L. and Mentha pulegium L. from Sardinia and to assess their efficacy on virulence factors for Candida albicans, particularly on the inhibition of the germ tube formation. The major compounds of the essential oils were carvone (62.9%) for M. spicata and pulegone (86.2%) for M. pulegium. The essential oil from M. spicata showed a more preeminent effect against Cryptococcus neoformans and the dermatophytes Trichophyton rubrum and T. verrucosum (0.32 μL/mL). Both oils were very effective in inhibiting C. albicans germ tube formation, at doses well below their MIC (0.16 μL/mL). |
| Databáze: | OpenAIRE |
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