Bone marrow ablation followed by allogeneic marrow grafting during first complete remission of acute nonlymphocytic leukemia

Autor:	S J, Forman, W E, Spruce, M J, Farbstein, J L, Wolf, E P, Scott, A P, Nademanee, J L, Fahey, T, Hecht, J A, Zaia, R A, Krance, D O, Findley, K G, Blume
Rok vydání:	1983
Předmět:	Patient Isolation Leukemia Bone Marrow Daunorubicin Immunology Cytarabine Humans Cell Biology Hematology Cyclophosphamide Biochemistry Whole-Body Irradiation Bone Marrow Transplantation
Zdroj:	Blood. 61:439-442
ISSN:	1528-0020 0006-4971
DOI:	10.1182/blood.v61.3.439.439
Popis:	Of 33 patients who had undergone allogeneic bone marrow transplantation during first complete remission of acute nonlymphocytic leukemia, 21 patients have now been followed in continued complete remission for 6- 64 mo (median greater than 18 mo) without maintenance chemotherapy. The median age of the surviving patients is 27 yr. Transplant-related complications occurring throughout the first year after marrow grafting were fatal in 7 patients, and leukemic recurrence led to the death of 5 patients. The actuarial long-term disease-free survival is 60% and the actuarial remission rate is 79%.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003a17aea291e955af5d2cf66a75f28f https://doi.org/10.1182/blood.v61.3.439.439 Zobrazit plný text záznamu