Molecular immunobiology of macrophages: recent progress
| Autor: | Siamon Gordon, David R. Greaves, Anthony G. Doyle, Sandra Clarke |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Macrophage colony-stimulating factor
medicine.drug_class Macrophages Immunology Receptors Cell Surface Biology Acquired immune system Monoclonal antibody Immunity Granulocyte macrophage colony-stimulating factor receptor medicine Animals Humans Immunology and Allergy Macrophage Secretion Tumor necrosis factor alpha Molecular Biology |
| Zdroj: | Current Opinion in Immunology. 7:24-33 |
| ISSN: | 0952-7915 |
| DOI: | 10.1016/0952-7915(95)80025-5 |
| Popis: | Macrophage molecules involved in adhesion, signalling, secretion and interactions with pathogens and T-helper lymphocytes have been cloned and defined using monoclonal antibodies and genetic disruption. Studies of the regulation of macrophage differentiation and activation by cytokines have yielded insights into the heterogeneity of their functions in natural and acquired immunity, including immunity to infections by mycobacteria and HIV. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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