Clinical Implication of Coronary Artery Calcium Score in Survivors of Out-of-Hospital Cardiac Arrest
| Autor: | Munemitsu Otagaki, Tetsuro Sugiura, Hiroshi Matsumoto, Hiromi Kin, Mitsuru Yokoi, Hiroki Shibutani, Ichiro Shiojima, Kenichi Fujii, Koichiro Matsumura, Yoshihiro Yamamoto |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Resuscitation Out-of-hospital cardiac arrest Predictive marker Multivariate analysis Critical Care business.industry Coronary artery calcium score Left bundle branch block ST elevation Original article General Medicine Acute myocardial infarction medicine.disease Out of hospital cardiac arrest Internal medicine Cardiology Medicine population characteristics Myocardial infarction cardiovascular diseases business |
| Zdroj: | Circulation Reports |
| ISSN: | 2434-0790 |
| Popis: | Background: The aim of this study was to evaluate the clinical ability of coronary artery calcium (CAC) score to identify acute myocardial infarction (AMI) in survivors of out-of-hospital cardiac arrest (OHCA). Methods and Results: We studied 180 consecutive survivors of OHCA who underwent immediate non-contrast computed tomography (CT) and coronary angiography. Seventy-one patients had ST elevation or left bundle branch block (LBBB; group 1) and 109 patients did not have ST elevation or LBBB (group 2) on post-resuscitation electrocardiogram (ECG). CAC score was significantly higher in AMI compared with non-AMI in groups 1 and 2. The optimal cut-off of CAC score to identify AMI was 11.5 (sensitivity, 80%; specificity, 71%) in group 1, and 27.4 (sensitivity, 80%; specificity, 76%) in group 2. On multivariate analysis, CAC score was the strongest predictive marker of AMI (OR, 10.91; 95% CI: 6.00-25.97). In addition, CAC score was an independent predictor of 30-day survival (OR, 0.38; 95% CI: 0.15-0.95). Conclusions: Evaluation of CAC is a useful method to identify AMI in survivors of OHCA, regardless of ST changes on post-resuscitation ECG. |
| Databáze: | OpenAIRE |
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