Treatment With Cholecalciferol Leads to Increase Of Selected Semen Parameters in Young Infertile Males: Results of a 6-month Interventional Study

Autor:	I, Bartl, M, Ondrušová, M, Kužma, P, Jackuliak, A, Gažová, J, Kyselovič, J, Payer
Rok vydání:	2021
Předmět:	Adult Male endocrine system Sperm Count urogenital system Physiology Articles Vitamins General Medicine Spermatozoa Semen Dietary Supplements Sperm Motility Humans Female Prospective Studies Vitamin D Infertility Male Cholecalciferol
Zdroj:	Physiol Res
ISSN:	1802-9973 0862-8408
DOI:	10.33549/physiolres.934781
Popis:	High incidence of infertility along with low vitamin D levels was detected in otherwise healthy young men. The aim is to observe the effect of vitamin D supplementation on semen parameters as assessed by semen analysis in infertile men. In total, 45 men (mean age 36.6 years) in consecutive order were included, of whom 34 finished the study. Subjects were supplemented by vitamin D (cholecalciferol) 2500 IU/day. Vitamin D levels were assessed by HPLC. Semen analysis was performed strictly following 2010 WHO guidelines. Study periods were baseline and month 6. During follow-up, 20 %, 7.4 %, 22 % and 0.7 % increase in serum vitamin D levels, progressive sperm motility, sperm concentration and sperm morphology, respectively, were observed (all p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0033b8228cc52a799f709723e89b0bb6 https://doi.org/10.33549/physiolres.934781 Zobrazit plný text záznamu