Pepsinogen 7 as an indicator of neonatal maturity: Preliminary studies
| Autor: | Bernard T. Ferrari, Philip L. Townes |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
Electrophoresis
Pediatrics medicine.medical_specialty media_common.quotation_subject Birth weight Urinary system Population Chromosome Disorders Gestational Age Trisomy Physical examination Kidney Excretion Pepsin Pregnancy medicine Birth Weight Humans education media_common Chromosome Aberrations education.field_of_study Pepsinogens biology medicine.diagnostic_test business.industry Infant Newborn Maturity (psychological) Pediatrics Perinatology and Child Health biology.protein Female business Hospital stay Infant Premature |
| Zdroj: | The Journal of Pediatrics. 80:809-814 |
| ISSN: | 0022-3476 |
| DOI: | 10.1016/s0022-3476(72)80136-7 |
| Popis: | Qualitative electrophoretic patterns of urinary pepsinogens (Pg1 to Pg7) were studied in two infant populations. Population 1 included 54 neonates judged to be full-term by expected date of confinement, birth weight, and physical examination. Population 2 included 17 neonates judged premature by identical criteria. Seventy-four per cent of Population 1 were nonexcretors by the end of the first week of life. With one exception, all infants in Population 2 were excretors during the first postnatal week. With further observation throughout their hospital stay, 15 infants continued to be excretors, and one showed transition to nonexcretor status during the last week of hospital stay. Since a previous study of a large nonneonatal population has shown that Pg7 is not normally excreted, excretion of Pg7 appears to be associated with prematurity. Nonexcretion or transition to nonexcretion appears to be associated with term maturity. Pg7 may therefore provide a useful biochemical index of neonatal maturity. |
| Databáze: | OpenAIRE |
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