Adrenal insufficiency in a child following unilateral excision of a dual-hormone secreting phaeochromocytoma

Autor: Aiden Lee, Maria P. Stack, Paul L. Hofman, Benjamin J Wheeler, Annika Sjoeholm, Chaey Leem, Cassandra Li
Rok vydání: 2015
Předmět:
Zdroj: Endocrinology, Diabetes & Metabolism Case Reports
ISSN: 2052-0573
DOI: 10.1530/edm-15-0041
Popis: Summary Phaeochromocytomas are a rare clinical entity, with dual hormone-secreting lesions particularly uncommon, seen in Learning points Dual hormone secreting phaeochromocytomas with ACTH/or a precursor may cause secondary adrenal insufficiency following surgical removal. The concurrent features of Cushing's syndrome can be mild and easily overlooked presenting diagnostic and management pitfalls. As concomitant syndromes of hormone excess are rare in phaeochromocytomas; the diagnosis requires a high index of suspicion. Serial/diurnal cortisol levels, ACTH measurement +/− low dose dexamethasone suppression (when clinically stable, appropriate adrenergic blockade in place, and well supervised), can all be considered as needed.
Databáze: OpenAIRE