Mycenolide A, new butenolide from a marine sediment-derived bacterium Streptomyces sp. 4054
| Autor: | Josiane A Monteiro de Oliveira, David E. Williams, Debora Cristina Baldoqui, Raymond J. Andersen, Maria Helena Sarragiotto |
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| Rok vydání: | 2019 |
| Předmět: |
Circular dichroism
biology 010405 organic chemistry Stereochemistry Chemistry Organic Chemistry Plant Science Bacillus subtilis biology.organism_classification Mass spectrometry Antimicrobial 01 natural sciences Biochemistry Streptomyces 0104 chemical sciences Analytical Chemistry 010404 medicinal & biomolecular chemistry Marine bacteriophage Bacteria Butenolide |
| Zdroj: | Natural product research. |
| ISSN: | 1478-6427 |
| Popis: | Streptomyces sp. 4054, isolated from marine sediments, produced a new butenolide, mycenolide A (1), along with five known butenolide derivatives (2-6). The structures of the compounds were established based on 1D- and 2D-NMR spectroscopic analysis, circular dichroism, and mass spectrometry data. The antimicrobial activity of the crude extract of the marine bacteria Streptomyces sp. 4054 was evaluated, showing good results against Bacillus subtilis and MRSA. |
| Databáze: | OpenAIRE |
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