Iatrogenic and spontaneous preterm birth in England: A population-based cohort study

Autor: Harriet, Aughey, Jennifer, Jardine, Hannah, Knight, Ipek, Gurol-Urganci, Kate, Walker, Tina, Harris, Jan, van der Meulen, Jane, Hawdon, Dharmintra, Pasupathy, Kirstin, Webster
Rok vydání: 2022
Předmět:
Zdroj: BJOG : an international journal of obstetrics and gynaecologyREFERENCES. 130(1)
ISSN: 1471-0528
Popis: open access article Objective: To describe the rates of and risk factors associated with iatrogenic and spontaneous preterm birth and the variation in rates between hospitals. Design: Cohort study using electronic health records. Setting: English National Health Service. Population: Singleton births between 1st April 2015 and 31st March 2017. Methods: Multivariable Poisson regression models were used to estimate adjusted risk ratios (adjRR) to measure association with maternal demographic and clinical risk factors. Main outcome measures: Preterm births (40 1.59 (1.50, 1.69)), and previous caesarean (adjRR 1.88 (1.83, 1.95)). Spontane-ous preterm birth was less common in women with a higher BMI (adjRR BMI>40 0.77 (0.70, 0.84)) and in women with a previous caesarean (adjRR 0.87 (0.83, 0.90)). More variation be-tween NHS hospital trusts was observed in rates of iatrogenic, compared to spontaneous, pre-term births. Conclusions: Just over half of all preterm births resulted from iatrogenic intervention. Iatro-genic births have overlapping but different patterns of maternal demographic and clinical risk factors to spontaneous preterm births. Iatrogenic and spontaneous sub-groups should therefore be measured and monitored separately, as well as in aggregate, to facilitate different preven-tion strategies. This is feasible using routinely acquired hospital data.
Databáze: OpenAIRE