Relationship of transforming growth factor-beta(1) with tumour necrosis factor-alpha and endothelial activation in patients with stable renal transplantation
| Autor: | Alessandro Palermo, Marco Guarneri, Anna Vadalà, Giovanni Cerasola, Francesco Vaccaro, Santina Cottone, Rosalia Arsena, Chiara Briolotta, Giuseppe Mulè |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors medicine.medical_treatment Intercellular Adhesion Molecule-1 Renal function Vascular Cell Adhesion Molecule-1 Transforming Growth Factor beta1 Internal medicine medicine Humans Renal Insufficiency Chronic Kidney transplantation Inflammation biology Cell adhesion molecule business.industry Tumor Necrosis Factor-alpha C-reactive protein Graft Survival General Medicine Transforming growth factor beta Middle Aged medicine.disease Kidney Transplantation Transplantation Endocrinology Cytokine C-Reactive Protein Cross-Sectional Studies Nephrology Case-Control Studies Hypertension biology.protein Endothelium Vascular business Biomarkers Glomerular Filtration Rate |
| Zdroj: | Nephrology (Carlton, Vic.). 13(2) |
| ISSN: | 1440-1797 |
| Popis: | SUMMARY: Aim: To evaluate whether or not transforming growth factor-beta1 is related to inflammation markers and to intercellular and vascular cell adhesion molecules in patients with stable renal transplantation. Methods: Serum concentrations of transforming growth factor-beta1, tumour necrosis factor-alpha, C-reactive protein and adhesion molecules were analysed in 33 renal transplanted patients, 33 patients with chronic renal insufficiency (matched to the transplanted group for level of renal function), and 33 hypertensives with normal renal function. anova, Student's t-test and simple regression analysis were used to analyse the data. Results: Transplanted patients showed higher values than hypertensives of transforming growth factor-beta1, tumour necrosis factor-alpha, C-reactive protein and adhesion molecules (P |
| Databáze: | OpenAIRE |
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