Spiroheterocycles from reaction of arylnitrile oxides with some (Z)-3-arylidene-2(3H)-benzofuranones. New access to orthohydroxyphenylisoxazoline esters
| Autor: | Nafaa Jgham, Karin Monnier‐Jobe, Mohamed B. Rammah, Joël Vebrel, Moheddine Askri, Kabula Ciamala |
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| Přispěvatelé: | Faculté des Sciences de Monastir (FSM), Université de Monastir - University of Monastir (UM), Univers, Transport, Interfaces, Nanostructures, Atmosphère et environnement, Molécules (UMR 6213) (UTINAM), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS), Institut Bisontin en Sciences Fondamentales (IBSF), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Laboratoire de Chimie des Matériaux et Interfaces (EA 474) (LCMI) |
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Pharmacology
Ethanol 010405 organic chemistry Chemistry Organic Chemistry Regioselectivity Hydrochloric acid General Medicine 010402 general chemistry 01 natural sciences Cycloaddition Analytical Chemistry 0104 chemical sciences 3. Good health chemistry.chemical_compound Organic chemistry [CHIM]Chemical Sciences ComputingMilieux_MISCELLANEOUS |
| Zdroj: | Heterocycles Heterocycles, The Japan Institute of Heterocyclic Chemistry, 2007, 71 (2), pp.289-303. ⟨10.3987/COM-06-10918⟩ |
| ISSN: | 0385-5414 1881-0942 |
| DOI: | 10.3987/COM-06-10918⟩ |
| Popis: | Some 4-substituted arylnitrile oxides and (Z)-3-arylidene-2(3H)-benzo-furanones undergo 1,3-dipolar cycloaddition reactions to give exclusively spirodihydroisoxazoles. These spiroadducts have be opened to the corresponding ethyl 3,4-diaryl-5-(orthohydroxyphenyl)-4,5-dihydroisoxazoline-5-carboxylates by the action of concentrated hydrochloric acid at reflux in ethanol. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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