Predialysis serum phosphate and intradialytic hypotension
| Autor: | Finnian R. Mc Causland, João Sérgio Neves, Patrick B. Reeves, Sushrut S. Waikar, Simon Correa, Katherine Scovner Ravi, Suraj Sarvode Mothi |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Blood Pressure Gastroenterology law.invention Phosphates Randomized controlled trial law Renal Dialysis Internal medicine medicine Humans Prospective Studies Prospective cohort study Dialysis business.industry Hematology Blood pressure Quartile Nephrology Cohort Kidney Failure Chronic Hemodialysis Hypotension business Complication |
| Zdroj: | Hemodialysis international. International Symposium on Home HemodialysisREFERENCES. 26(1) |
| ISSN: | 1542-4758 |
| Popis: | INTRODUCTION Intradialytic hypotension (IDH) is a common complication of hemodialysis (HD) and is associated with excess morbidity and mortality. Higher serum phosphate is associated with adverse cardiovascular outcomes in maintenance HD patients; however, its association with IDH has not previously been assessed. METHODS This is an analysis of a prospective cohort of 969 HD patients (80,968 HD sessions) receiving HD at a large dialysis organization (LDO) and a post-hoc analysis of 1838 HD patients (10,594 HD sessions) in the Hemodialysis study (HEMO), a multicenter randomized controlled trial that examined standard or high-dose HD and low-flux or high-flux membranes. Unadjusted and adjusted mixed effects regression models were fit to determine the association of pre-HD serum phosphate with IDH, defined as a nadir intra-HD systolic blood pressure (SBP) |
| Databáze: | OpenAIRE |
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