Ultralow Voltage, OTFT-Based Sensor for Label-Free DNA Detection
| Autor: | Lai, S. [ 1 ], Demelas M. [ 1, 2 ], Casula G. [ 1, Cosseddu P. [ 1, Barbaro M. [ 1 ], Bonfiglio A. [ 1 |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Detection limit
Materials science Organic field-effect transistor Transistors Electronic Oligonucleotide business.industry Mechanical Engineering Electric Conductivity organic chemosensor organic field effect transistor organic biosensor DNA hybridization sensor ultra-low voltage device Nucleic Acid Hybridization DNA Electric charge Transduction (genetics) Electricity Mechanics of Materials Optoelectronics General Materials Science Field-effect transistor Organic Chemicals business Selectivity Voltage |
| Zdroj: | Advanced materials (Weinh., Print) 25 (2013): 103. doi:10.1002/adma.201202996 info:cnr-pdr/source/autori:Lai, S. [ 1 ], Demelas M. [ 1,2 ], Casula G. [ 1,2 ], Cosseddu P. [ 1,2 ], Barbaro M. [ 1 ], Bonfiglio A. [ 1,2 ]/titolo:Ultralow Voltage, OTFT-Based Sensor for Label-Free DNA Detection/doi:10.1002%2Fadma.201202996/rivista:Advanced materials (Weinh., Print)/anno:2013/pagina_da:/pagina_a:103/intervallo_pagine:103/volume:25 |
| DOI: | 10.1002/adma.201202996 |
| Popis: | An organic ultralow voltage field effect transistor for DNA hybridization detection is presented. The transduction mechanism is based on a field-effect modulation due to the electrical charge of the oligonucleotides, so label-free detection can be performed. The device shows a sub-nanometer detection limit and unprecedented selectivity with respect to single nucleotide polymorphism. |
| Databáze: | OpenAIRE |
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