Prostate Artery Embolization for Complete Urinary Outflow Obstruction Due to Benign Prostatic Hypertrophy

Autor: Simon C.H. Yu, Peter K. F. Chiu, Chi Hang Yee, Esther H. Y. Hung, Chi-Fai Ng, Carmen C.M. Cho
Rok vydání: 2016
Předmět:
Male
medicine.medical_specialty
medicine.medical_treatment
Prostate artery
Prostatic Hyperplasia
030232 urology & nephrology
Urology
urologic and male genital diseases
030218 nuclear medicine & medical imaging
Muscle hypertrophy
Embolization
03 medical and health sciences
0302 clinical medicine
Urinary outflow obstruction
Prostate
Artery embolization
medicine
Humans
Radiology
Nuclear Medicine and imaging
Prospective Studies
Clinical Investigation
Acute retention of urine
Aged
Aged
80 and over
Urinary symptoms
Urinary retention
business.industry
Angiography
Middle Aged
Urinary Retention
Embolization
Therapeutic
Magnetic Resonance Imaging
Benign prostatic hypertrophy
Surgery
Catheter
Treatment Outcome
medicine.anatomical_structure
Radiology Nuclear Medicine and imaging
Fluoroscopy
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Follow-Up Studies
Zdroj: Cardiovascular and Interventional Radiology
ISSN: 1432-086X
0174-1551
DOI: 10.1007/s00270-016-1502-3
Popis: Background We aimed to evaluate the effectiveness of PAE in weaning of catheter and relieving obstructive urinary symptoms in patients with acute urinary retention (AUR) due to benign prostatic hypertrophy (BPH) and failed trial without catheter (TWOC). Materials and Methods In this prospective study approved by the institutional review board, a signed informed consent was obtained. Eighteen consecutive patients with AUR due to BPH and failed TWOC were recruited. Nineteen consecutive patients with BPH but without AUR were recruited as a control. Patients with CTA evidence of arterial occlusion or significant stenosis along the prostate artery access path were excluded. PAE was performed using microspheres (100–300 μm diameter). Outcome assessment included successful weaning of catheter in 2 weeks, procedure-related complications, change of symptomatology and urodynamic findings at 1 month as compared to baseline, percent non-perfused prostate volume, and prostate volume reduction on MRI at 2 weeks. Results Two patients in the study group and four in the control group were excluded due to arterial pathology. Embolization of bilateral prostate arteries was achieved in all patients in both the groups (100%). There was no complication. The catheter was successfully weaned in 87.5% (14/16) of patients within 14 days in the treatment group. There was no significant difference in patient demographics, prostate characteristics, and all outcome assessment parameters between both the groups. Conclusions PAE was probably safe and effective in weaning of catheter and relieving obstructive urinary symptoms in patients due to BPH, with treatment outcomes comparable to those without AUR.
Databáze: OpenAIRE
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