Three Methods for the Solution Phase Synthesis of Cyclic Peptides

Autor:	Lukas Junk, Angelika Ullrich, Uli Kazmaier
Rok vydání:	2021
Předmět:	Depsipeptide chemistry.chemical_classification Chain (algebraic topology) chemistry High interest Biological property food and beverages Peptide bond Peptide Combinatorial chemistry Cyclic peptide Solution phase synthesis
Zdroj:	Methods in Molecular Biology ISBN: 9781071616888
DOI:	10.1007/978-1-0716-1689-5_4
Popis:	Cyclic peptides, which often exhibit interesting biological properties, can be obtained by macrolactamization of adequately protected linear peptide chains. Because of the remarkable biological properties, methods for the efficient cyclization of peptides are of high interest. We herein describe three different protocols for the cyclization of peptides and depsipeptides via amide bond formation. These methods can, in principal, be applied to any linear peptide chain.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fffed2657c6ba3ffe86a6d780fee1e8d https://doi.org/10.1007/978-1-0716-1689-5_4 Zobrazit plný text záznamu