Direct MYD88L265P gene detection for diffuse large B-cell lymphoma (DLBCL) via a miniaturised CRISPR/dCas9-based sensing chip

Autor: Weihan Sun, Wei Guo, Zhiyi Liu, Sennan Qiao, Ziming Wang, Jiayu Wang, Lingxuan Qu, Liang Shan, Fei Sun, Shuping Xu, Ou Bai, Chongyang Liang
Rok vydání: 2022
Předmět:
Zdroj: Lab on a Chip. 22:768-776
ISSN: 1473-0189
1473-0197
DOI: 10.1039/d1lc01055g
Popis: CRISPR/dCas9 technology integrated with electrochemical detection was developed for ultrasensitive and fast gene mutation detection of diffuse large B-cell lymphoma above a dCas9/sgRNA modified porous anodised aluminium sensing chip.
Databáze: OpenAIRE