Effect of enkephalins on associative processes in parietal cortical neurons
Autor: | V. V. Yasnetsov, V. A. Pravdivtsev |
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Rok vydání: | 1990 |
Předmět: | |
Zdroj: | Bulletin of Experimental Biology and Medicine. 110:1147-1150 |
ISSN: | 1573-8221 0007-4888 |
Popis: | Experiments on cats examined the effect of met- and leu-enkephalins on the process of learning of the parietal associative cortex neurons (field 5). It has been shown that conditioned electrical stimulation of the pyramidal tract axons with nociceptive reinforcement evoked plastic changes of responses in 35 neurons. It was found that the effect of microiontophoretically applied enkephalins on these neurons depend on the time of iontophoretic application. When endogenous opioid peptides were applied up to 30-40 min they inhibited the process of elaboration of temporary connection. |
Databáze: | OpenAIRE |
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