State-of-the-art molecular genetic testing for the diagnosis of viral infections
| Autor: | Marina Samotrueva, G.A. Rostoshvili, O. A. Bashkina, Anna Yasenyavskaya, K. Sh. Arnaudova |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Russian Medical Inquiry. 5:497-502 |
| ISSN: | 2686-9918 2587-6821 |
| DOI: | 10.32364/2587-6821-2021-5-7-497-502 |
| Popis: | High contagiousness and rapid spread of viral infections highlight the importance of their timely clinical diagnosis. There is a current need to gain in-depth knowledge of viral agents’ origin, routes, and evolution to predict and prevent viral diseases. The introduction of advanced molecular genetic testing made this possible. Laboratories worldwide develop and manufacture urgently needed test kits for rapidly detecting infections since asymptomatic cases favor further dissemination of these diseases. Over the last year, the active development of diagnostic kits for COVID-19 contributed to the improvement of molecular genetic testing, particularly for mass and screening testing. RT-PCR is widely applied to detect viral RNA. Meanwhile, other tests for nucleic acids, e.g., isothermal amplification, microarray hybridization, amplicon metagenome sequencing, and CRISPR, are now introduced into daily practice. KEYWORDS: viruses, diagnostics, molecular genetic testing, polymerase chain reaction, RNA. FOR CITATION: Arnaudova K.Sh., Yasenyavskaya A.L., Rostoshvili G.A. et al. State-of-the-art molecular genetic testing for the diagnosis of viral infections. Russian Medical Inquiry. 2021;5(7):497–502 (in Russ.). DOI: 10.32364/2587-6821-2021-5-7-497-502. |
| Databáze: | OpenAIRE |
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