Popis: |
Analyses of sensory nerve action potentials (SNAP) and somatosensory evoked potentials (SSEPs) provide an important physiologic measure of the sensory system because electrophysiologic abnormalities depend on the kind and degree of damage in individual fibers within the nerve. In segmental demyelination, for example, failure to activate the next node of Ranvier in some fibers results in diminution of SNAP. The size of the recorded response, however, does not necessarily change in proportion to the number of functional axons; a major reduction in amplitude or area can result from physiologic desynchronization of the axonal volleys [1, 6, 8]. |